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first_img And the second panel box, before and after. [Photo & text: sa] February 25, 2005 Continuation from 2/23 – Arcosanti site electrician Michael Bittman, aka Dr. Sparks, at the completed, well labeled wall panel. [Photo & text: sa] There are some exceptions to the electric lines connected to the public grid. A small solar plant in Unit 8, see installation of the supporting solar panel reported on 6/16/03, supplies power to Units 8, 9 and 10, as well as to the lighting of hallways and walkways all through the East Crescent. More of this on 3/2. [Photo & text: sa]last_img read more

first_imgThese insights have the potential to make a big difference to how we treat sexual disorders in male babies in future – and are also relevant to the whole debate about male and female identity.Paul Fowler, Study Author. Source:Fowler, P. Move over testosterone, another hormone is also vital for making boys – and it doesn’t come from the testes. The Conversation. By Sally Robertson, B.Sc.Feb 15 2019Reviewed by Kate Anderton, B.Sc. (Editor)A new study has revealed that testosterone, which is produced and released by the testes, is not the only hormone involved in fetal development of the male penis. It is now thought that the masculinization process also involves a hormone called androsterone, which originates in other tissues, including the placenta.Sebastian Kaulitzki | ShutterstockThe results not only shed light on a previously unknown “backdoor” pathway of masculinization, but could also explain the link between placental dysfunction and disorders of male genital development.center_img During male fetal development, testosterone from the testes is converted into the male sex hormone 5α-dihydrotestosterone (DHT) by the genital tubercle – the primordial structure that either develops into a penis or clitoris.In one in a few thousand cases, babies are born with “ambiguous” genitalia, where their gender is not quite clear. Previously, the understanding was that this is caused by problems associated with testosterone.However, recent studies have shown that penis development also relies on a second, alternative or “backdoor” pathway, where DHT is produced independently of testosterone from the testicles. However, the details of this other pathway remained unclear, including the source DHT.As reported in the journal PLOS Biology, Fowler and collaborators in Glasgow, France and Sweden have conducted a study that explains more about this second process.Using mass spectrometry, the team measured levels of steroid hormones in fetal plasma and tissue during the second trimester – the most vital phase for penis development. The researchers also measured gene expression in tissues known to be involved in hormone synthesis.The study revealed that the hormone androsterone, which can also be converted to DHT, was the main steroid hormone present in the blood of the male fetus and that both androsterone and testosterone were present at lower levels in the female circulation.In addition, the enzymes required to convert androsterone to DHT were mainly present in non-gonadal tissues including the placenta and the liver.Given that androsterone can be made from progesterone, Fowler and colleagues suggest that placental progesterone is the androsterone source in the alternative pathway.Our results demonstrate that masculinization of the male fetus depends not only on the testes, but also on other tissues, especially the placenta. They also suggest an explanation for why disorders of placental insufficiency can lead to hypospadias and other abnormalities of growth of the male external genitalia.”last_img read more

first_imgReviewed by Kate Anderton, B.Sc. (Editor)Apr 15 2019Results from a large clinical trial indicate that patients with rheumatoid arthritis are likely to experience the same level of cardiovascular benefits from statins as other individuals, without additional risks. The findings appear in Arthritis & Rheumatology, an official journal of the American College of Rheumatology.Patients with rheumatoid arthritis have an approximately 50 percent higher risk of experiencing cardiovascular events such as heart attack and stroke compared with the general population. By lowering LDL cholesterol, statins are known to help prevent cardiovascular events in certain high-risk individuals, but it’s unclear whether they are safe and effective for patients with inflammatory conditions such as rheumatoid arthritis.To investigate the potential risks and benefits of statins in moderate risk patients with rheumatoid arthritis, researchers designed the Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients with Rheumatoid Arthritis (TRACE RA), a multi-center, randomized, double-blind trial comparing the statin atorvastatin with placebo.The trial included 3,002 patients with rheumatoid arthritis who were over aged 50 years or had rheumatoid arthritis for more than 10 years, without clinical atherosclerosis, diabetes, or myopathy. Patients were randomized to receive atorvastatin 40mg daily or placebo.During a median follow-up of 2.5 years, 1.6 percent of patients who received atorvastatin and 2.4 percent of patients receiving placebo experienced cardiovascular death, heart attack, stroke, transient ischemic attack, or any arterial revascularization. After adjustments, there was a 40 percent lower risk of cardiovascular events for patients taking atorvastatin, although the difference was not statistically significant. This was because the overall rate of events was low.Related StoriesResearchers identify new clues on tissue damage in rheumatoid arthritis and lupusFirst safe, reliable, noninvasive way to monitor rheumatoid arthritisResearchers develop NO-scavenging hydrogel for treatment of rheumatoid arthritisAt the end of the trial, patients taking atorvastatin had significantly lower LDL cholesterol as well as significantly lower levels of C-reactive protein, a marker of inflammation, compared with patients taking placebo. Adverse events in the atorvastatin and placebo groups were similar.The paper’s lead author is Professor George Kitas of Dudley Group NHS Foundation Trust, while co-senior authors are Professor Jill Belch of the University of Dundee and Professor Deborah Symmons of the University of Manchester.”The trial found that the statin reduced levels of cholesterol by similar amounts as has been seen in other populations studied. The results also show that it is as safe for patients with rheumatoid arthritis to take statins as for the general population,” said Prof. Symmons. “In addition, because of the low overall rate of cardiovascular events in the trial population, there is no indication for all patients with rheumatoid arthritis to be prescribed a statin. This is unlike diabetes where the great majority of patients are recommended to take a statin.”The study authors recommend that patients with rheumatoid arthritis be prescribed statins according to national or local guidelines for managing cardiovascular risk in the general population.An accompanying editorial notes that the study provides information that will be useful for researchers and clinicians who focus on rheumatoid arthritis, and the results may be helpful when considering cardiovascular risk across other rheumatic diseases. Source:https://newsroom.wiley.com/press-release/arthritis-rheumatology/large-clinical-trial-finds-statins-safe-and-likely-effective-prlast_img read more

first_img The 25 Most Mysterious Archaeological Finds on Earth Photos: Viking Warrior Is Actually a Woman 30 of the World’s Most Valuable Treasures That Are Still Missing The discovery of cannabis pollen near a Viking settlement in Newfoundland raises the question of whether the Vikings were smoking or eating pot while exploring North America. The researchers also found evidence the Vikings occupied this outpost for more than a century, way longer than previously believed. Located in northern Newfoundland, the site of L’Anse aux Meadows was founded by Vikings around A.D. 1000. Until now, archaeologists believed that the site was occupied for only a brief period. The new research, published today (July 15) in the journal Proceedings of the National Academy of Sciences, suggests that the Vikings lived there possibly into the 12th or even the 13th century. [In Photos: Viking Outposts Possibly Found in Canada]Headbutting Tiny Worms Are Really, Really LoudThis rapid strike produces a loud ‘pop’ comparable to those made by snapping shrimps, one of the most intense biological sounds measured at sea.Your Recommended PlaylistVolume 0%Press shift question mark to access a list of keyboard shortcutsKeyboard Shortcutsplay/pauseincrease volumedecrease volumeseek forwardsseek backwardstoggle captionstoggle fullscreenmute/unmuteseek to %SPACE↑↓→←cfm0-9接下来播放Why Is It ‘Snowing’ Salt in the Dead Sea?01:53 facebook twitter 发邮件 reddit 链接https://www.livescience.com/65940-were-vikings-smoking-pot-in-newfoundland.html?jwsource=cl已复制直播00:0000:3500:35  Bog finds In August 2018, an archaeological team excavated a peat bog located nearly 100 feet (30 meters) east of the Viking settlement at L’Anse aux Meadows. They found a layer of “ecofacts” — environmental remains that may have been brought to the site by humans — that were radiocarbon dated to the 12th or 13th century. These ecofacts include remains of two beetles not native to Newfoundland — Simplocaria metallica, from Greenland, and Acidota quadrata, from the Arctic. The layer also held pollen from Juglans (walnuts) and from Humulus (cannabis), two species that don’t naturally grow at L’Anse aux Meadows; rather, the Vikings could have picked up all of these plant and animal species when they sailed south. [Photos: 10th-Century Viking Tomb Unearthed in Denmark] They also found the remains of dung from grazing caribou, as well as remains of wood and charcoal. The layer from the peat bog is similar to other “cultural layers from across the Norse North Atlantic,” the archaeological team wrote in the journal article. More evidence Additionally, the archaeologists performed Bayesian analysis — a type of statistical analysis — on radiocarbon dates from artifacts previously excavated at L’Anse aux Meadows. That analysis also suggested Viking occupation for up to 200 years. “This does not imply a continuous occupation,” the researchers wrote, noting that the Vikings could have abandoned and reoccupied L’Anse aux Meadows when it suited them. Did the Vikings use pot in Newfoundland? The finding of cannabis pollen raises the question of whether the Vikings used cannabis for making clothes or for medicinal-recreational purposes while they explored North America. Paul Ledger, the lead author of the paper and a postdoctoral fellow at Memorial University of Newfoundland urged caution on the interpretation of the findings, noting that pollen can easily be carried by the wind. Ledger urged caution on the interpretation of the findings, noting that pollen can easily be carried by the wind. It’s also possible that some of the other “ecofacts” were brought to the peat bog by indigenous peoples who lived in Newfoundland, and not by the Vikings. [Fierce Fighters: 7 Secrets of Viking Seamen] Ultimately, “the results presented here [in the journal article] pose more questions than answers,” the archaeological team wrote. Reaction from other Viking researchers Viking researchers not affiliated with the research team urged caution about the results. “I think it is too early to draw any conclusions,” said Birgitta Wallace, a senior archaeologist emerita with Parks Canada who has done extensive research on the Vikings in North America. Wallace told Live Science that she isn’t convinced that the Vikings left behind these ecofacts. “I think it is highly unlikely that the Norse [another word for Vikings] would have returned in the 12th and 13th centuries, as there are no structures on the site from that period that could be Norse,” Wallace said. “We do know that there were indigenous people, ancestors of the Beothuk, on the site at that time.” Patricia Sutherland, a visiting scientist at the Canadian Museum of Nature who has also done extensive research on the Vikings in North America, said that while the Vikings could have been in Newfoundland during the 12th or 13th centuries, it is too early to say for sure. “It seems premature to suggest such a scenario on the basis of the ‘ecofacts’ listed in the paper,” Sutherland said. It’s possible that some of the beetles and plant pollen found in the layer were brought to L’Anse aux Meadows by the Vikings around A.D. 1000, and they continued to flourish after the Vikings left, Sutherland said. The research team plans to continue their work at L’Anse aux Meadows in August, Ledger said. Editor’s note: This article was updated to fix a statement about the interpretation of the cannabis pollen. Originally published on Live Science.by Taboolaby TaboolaSponsored LinksSponsored LinksPromoted LinksPromoted LinksYou May LikeVikings: Free Online GamePlay this for 1 min and see why everyone is addicted!Vikings: Free Online GameUndoTruthFinder People Search SubscriptionOne Thing All Liars Have in Common, Brace YourselfTruthFinder People Search SubscriptionUndoKelley Blue Book2019 Lexus Vehicles Worth Buying for Their Resale ValueKelley Blue BookUndoArticles VallyDad Cuts Daughter’s Hair Off For Getting Birthday Highlights, Then Mom Does The UnthinkableArticles VallyUndoNucificTop Dr. Reveals The 1 Nutrient Your Gut Must HaveNucificUndoGundry MD Total Restore SupplementU.S. Cardiologist: It’s Like a Pressure Wash for Your InsidesGundry MD Total Restore SupplementUndolast_img read more

first_img Golf 07 Jul 2019 American Daly not allowed to use golf cart at British Open Golf 11 May 2019 Woods, Koepka, Molinari to tee off early in first round at PGA Northern Irishman Rory McIlroy and American Justin Thomas carded 67, while former champion Rickie Fowler was among just a handful of players to struggle, shooting 71. (Reporting by Andrew Both in Cary, North Carolina, editing by Ed Osmond) (Reuters) – Edoardo Molinari was among many to take advantage of ideal conditions at the Scottish Open on Thursday, vaulting into a four-way share of the first-round lead in North Berwick.Edoardo, older brother of reigning British Open champion Francesco, carded eight-under-par 63, a score matched by fellow Italian Nino Bertasio, American Matt Kuchar and France’s Romain Wattel at the Renaissance Club.While Francesco is having a week off to prepare for next week’s Open at Royal Portrush, Edoardo is attempting to qualify as one of the top three finishers this week not also already exempt.Soft conditions and little breeze left the course at the mercy of the field on a day when more than half the players broke 70. Related Newscenter_img Related News Golf 11 Jul 2019 Golf – Social media critics no problem but not granny, says Kuchar {{category}} {{time}} {{title}}last_img read more

first_img Tags / Keywords: Markets 27 Jun 2019 Trade-war winner Vietnam is now a target for Trump’s tariffs Related News Vietnam goes from trade war winner to Trump target. Economy Nation 08 Jul 2019 US not being clear of its priority targets in trade war with China Nation 10 Jul 2019 Malaysia has potential to profit from US-China trade war, says Azmin Related News {{category}} {{time}} {{title}} For manufacturers like IREX, Trump’s recent action means they can’t sit back either.”Our sales department is looking for new markets, so if the U.S. increases Vietnam tariffs it won’t impact IREX’s business much,” said Trang, the company’s COO.- Bloomberg HANOI: Americans are buying solar panels from Vietnam like never before, but local manufacturer IREX Energy JSC isn’t celebrating.After U.S. President Donald Trump slapped higher tariffs on China, production in neighbouring Vietnam went into overdrive. Chinese manufacturers, who face a 55% U.S. tariff on their goods, relocated some production to Vietnam, while local businesses saw a jump in orders. In June alone, U.S. imports of solar cells from Vietnam surged 656% from a year ago.That trade boom in everything from Ikea furniture to Nike Inc. shoes is now prompting more scrutiny from the US and making businesses like IREX concerned.”We are worried that the US may raise tariffs on our solar panels,” Pham Thi Thu Trang, the company’s chief operating officer, said from Ho Chi Minh City. “Though the U.S market is huge, it is a complicated market when it comes to its politics.”Communist Party-led Vietnam has steadily opened up to foreign investors over the years to become a manufacturing hub in the region, with household names like Samsung Electronics Co., Intel Corp. and Nestle SA setting up factories there. It’s that trade openness, as well as its low-cost labor and proximity to China, that’s helped Vietnam successfully navigate growing global protectionism as companies seek out refuges from the trade war.It’s very quickly climbed the ranks to become a significant U.S. trade partner. Vietnam’s annual trade surplus with the U.S. has exceeded $20 billion since 2014 and reached $40 billion last year, the highest in records going back to 1990, according to U.S. Census Bureau data. For the first five months of the year, the surplus is already 43% higher than a year ago at $21.6 billion.The Trump administration is now pressuring the nation of 97 million people to slash its trade surplus, threatening one of the world’s fastest-growing economies.Trouble began in May, when the U.S. Treasury added Vietnam to a watchlist of countries being monitored for possible currency manipulation. Then, in response to U.S. pressure, Vietnam announced a crackdown on Chinese exporters rerouting products through the Southeast Asian nation with fake Made-in-Vietnam labels to bypass Trump’s tariffs.Trump described Vietnam last month as “almost the single-worst abuser of everybody” when asked if he wanted to impose tariffs on the nation. And just last week, the U.S. slapped duties of more than 400% on steel imports from Vietnam which originated in South Korea and Taiwan.Vietnam officials have been left reeling. The government says it’s committed to buying more U.S. goods, from Boeing Co. jets to energy products to help narrow its trade surplus with the world’s largest economy. Prime Minister Nguyen Xuan Phuc last week told officials to monitor U.S. reactions to the nation’s monetary policy more closely.”They are very nervous and confused. They don’t know what Trump’s next move will be,” said Alexander Vuving, a professor at the Daniel K. Inouye Asia-Pacific Center for Security Studies in Hawaii.Vietnam has not been adept at responding to charges against its trading practices in Washington, where a cadre of lawyers are needed to quickly engage the government, said Nestor Scherbey, a licensed U.S. customs broker and consultant based in Ho Chi Minh City. “It’s like being charged in court and not showing up.”Cheap LabourCapital Economics Ltd. estimates that if Trump levied a 25% tariff on imports from Vietnam as he did with Chinese goods, Hanoi would see a 25% drop in export revenue, equivalent to more than 1% of the nation’s gross domestic product. That would erase the estimated 0.5 percentage-point gain it has had over the past year as a beneficiary of the trade war.Even before the trade tensions, Vietnam was benefiting from businesses looking for low-cost alternatives to China as wages there grew. That trend will likely continue, which should help to sustain Vietnam’s economic trajectory, according to Adam McCarty, chief economist with Mekong Economics in Hanoi.”It’s not going to stop the underlying economic motivation to move basic factory work from China to Vietnam,” he said. “China is getting too expensive.”Vietnam’s leaders have also long worked to buffer the country from trade shocks by hedging its reliance on any single market, including the U.S., the nation’s largest export destination. Vietnam has inked more than a dozen free trade agreements such as the just-signed deal with the European Union that will eliminate 99% of customs duties, and the revamped Trans-Pacific Partnership, which eventually provides duty-free access to markets such as Canada and Japan for many products.”Vietnam’s foreign policy for decades has been the opposite of what Groucho Marx said: he’d never want to join a club that would have him,” McCarty said. “The Vietnamese approach is to join every trade and investment club they possibly can.”last_img read more